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	<title>Health and Beauty</title>
	<link>http://www.spacandille.com</link>
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	<pubDate>Tue, 05 Jan 2010 22:18:31 +0000</pubDate>
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		<title>Blood issues are likely to cause ED</title>
		<link>http://www.spacandille.com/articles/blood-issues-are-likely-to-cause-ed.html</link>
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		<pubDate>Tue, 05 Jan 2010 22:18:31 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Articles]]></category>

		<category><![CDATA[Alcoholism]]></category>

		<category><![CDATA[Blood Circulation]]></category>

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		<category><![CDATA[Blood Problems]]></category>

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		<category><![CDATA[Causes Of Erectile Dysfunction]]></category>

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		<category><![CDATA[Sexual Potency]]></category>

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		<guid isPermaLink="false">http://www.spacandille.com/articles/blood-issues-are-likely-to-cause-ed.html</guid>
		<description><![CDATA[It is not big news that erectile dysfunction is not only psychological issue, rising from nervous problems such as depression, anxiety or stress. In fact, most cases of male impotence have different blood problems as the primary cause. Healthy state of blood vessels in your body, and in your penis particularly, is crucial for good [...]]]></description>
			<content:encoded><![CDATA[<p>It is not big news that erectile dysfunction is not only psychological issue, rising from nervous problems such as depression, anxiety or stress. In fact, most cases of male impotence have different blood problems as the primary cause. Healthy state of blood vessels in your body, and in your penis particularly, is crucial for good and effective functioning of the penis. So when getting to ED treatment, having a drug that has to do with overall blood circulation and the blood flow in the penis is really important. In some cases erectile dysfunction is a side-effect of the drugs you are currently taking for other health conditions such as depression. That&#8217;s why it is very important to choose the right kinds of medication and to know their side-effects.</p>
<p><strong>Health conditions that are likely to cause ED</strong></p>
<p>One of the most widely seen causes of erectile dysfunction is the damage to blood vessels and nervous tissue delivered by diabetes. Other medical conditions that are likely to cause erectile dysfunction include blood pressure issues, liver or kidney diseases, atherosclerosis, multiple sclerosis, testosterone level issues and damage to blood vessels and nervous tissue during surgeries in the penile area and the spinal chord. Impotence can also be caused by chronic substance abuse such as alcoholism or street drug addiction. Some drugs you are taking currently can also cause erectile dysfunction. These medications include common treatments for depression, chest pain, insomnia, overweight and ulcer. A quick fix of such conditions is likely to improve the degree of impotence but if the condition lasted for a longer period of time it will take a lot more to overcome its effects than simply taking a pill of a drug like <a href="http://www.36-hour-pills.com/blood-issues.html">Cialis</a> and hope it will solve all of your problems.</p>
<p><strong>Lifestyle strongly affects sexual potency</strong></p>
<p>Do you smoke often? Are you a regular at the local bar? Is your work stressful and you don&#8217;t get enough sleep on a regular basis? Eliminating all of these factors can significantly improve your sexual health. Men with heavy smoking and drinking habits are more prone to developing ED than non-smokers and non-drinkers. A recent two year study with participation of overweight men who had ED has shown impressive results of lifestyle change on sexual performance. During the course of the study, the participants had to follow a low-calorie diet, exercise on a regular basis, and kick off their nasty habits. As a result, about one third of the test subjects have shown dramatic improvement of the quality of their erections without using such drugs as <a href="http://www.36-hour-pills.com/">Cialis</a> at all. So make sure to change your lifestyle towards a healthier one first and maybe it will help you without having to use any additional medications. It all depends on how long you have been experiencing the negative effects of nicotine, alcohol, recreational drugs and unhealthy diet. The rule of thumb here is the longer you follow such a lifestyle, the harder it will be to get back to the normal and healthy one and get significant improvements. Still, it&#8217;s all possible so make sure to take that change towards a better and healthier way of living your life.</p>

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		<title>What are the main psychological causes of erectile dysfunction?</title>
		<link>http://www.spacandille.com/articles/what-are-the-main-psychological-causes-of-erectile-dysfunction.html</link>
		<comments>http://www.spacandille.com/articles/what-are-the-main-psychological-causes-of-erectile-dysfunction.html#comments</comments>
		<pubDate>Mon, 04 Jan 2010 22:18:39 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
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		<guid isPermaLink="false">http://www.spacandille.com/articles/what-are-the-main-psychological-causes-of-erectile-dysfunction.html</guid>
		<description><![CDATA[The pharmaceutical industry tries to sell you a basic idea - the idea that everything that goes wrong with you can be cured if you buy the right pill. Unfortunately this has never been, and never will be, true. The human mind is a complicated piece of equipment and, if there is a psychological problem, [...]]]></description>
			<content:encoded><![CDATA[<p>The pharmaceutical industry tries to sell you a basic idea - the idea that everything that goes wrong with you can be cured if you buy the right pill. Unfortunately this has never been, and never will be, true. The human mind is a complicated piece of equipment and, if there is a psychological problem, ordinary pills are useless. In the case of erectile dysfunction (ED), there are a number of different psychological and relationship issues that may have to be resolved before normal sexual activity can be resumed. Yet, the average doctor will concentrate on the biology and ignore the psychology. There are two reasons for this. There are impressive lab tests that justify fee income and can produce black-and-white results in ruling in, or eliminating, diseases and disorders. This can take money while making everyone in the healthcare industry look professionally competent. Secondly, many doctors are embarrassed if they have to start talking to their patients about sex. It burns up time and, unless the doctor has specific expertise, often produces poor outcomes (except, of course, in the size of the bill).</p>
<p>The last thirty years has seen a steady sexual revolution. You see this in a greater acceptance of feminism and the notion of gender equality. The woman&#8217;s right to choose also shows in the increasing use of oral contraceptives. Before the ED medications came on the market, counselors talked couples through their relationship problems. When the little blue pill appeared, everything when back to biology. Except the drugs do not cure relationship problems. Rightly or wrongly, many men have fixed ideas about how sex is supposed to happen. If something disturbs this, &#8220;my way or the highway&#8221; approach, this loss of control causes stress and ED appears. Often, the men affected are failing to match up to myths. They are the victims of misinformation.</p>
<p>Put simply, if men are not getting any satisfaction out of sex with their partners, they will avoid situations where sex can occur. The stress will be increased if there is another possible partner, or the men are interested in fetishes but afraid to mention them, or worried about their sexual orientation. A man who has lost interest in sex with his partner, for whatever reason, will find drugs of little help. But, if the underlying relationship is sound, the best of the three ED drugs to take is <a href="http://www.levitraguidance.com/">levitra</a>. It may well be necessary for the couple to go through therapy to resolve their personal issues but, with the support of medication, sexual activity may be restarted. This will require courage because, probably for the first time, the man will have to talk openly about his life, his work, his fears and how he thinks his sex life should run. Hopefully, his partner will be supportive during this time. It is counterproductive to be demanding and expect that, if you <a href="http://www.levitraguidance.com/more-about-levitra/main-psychological-causes.html">buy levitra</a>, everything will be better. Sex is more than producing an erection. It is about your mood and confidence in the relationship. Getting into that mood is the challenge.</p>

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		<title>Are men and women the same when it comes to pain?</title>
		<link>http://www.spacandille.com/articles/are-men-and-women-the-same-when-it-comes-to-pain.html</link>
		<comments>http://www.spacandille.com/articles/are-men-and-women-the-same-when-it-comes-to-pain.html#comments</comments>
		<pubDate>Sun, 03 Jan 2010 22:46:09 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Articles]]></category>

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		<category><![CDATA[Sex And Gender]]></category>

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		<guid isPermaLink="false">http://www.spacandille.com/articles/are-men-and-women-the-same-when-it-comes-to-pain.html</guid>
		<description><![CDATA[In these more modern times of sexual equality, it may not be politically correct to talk about differences between men and women. Unfortunately, the medical profession cannot ignore the increasing volume of scientific evidence that there are important differences, particularly when it comes to pain management. In this, it is important to distinguish between biological [...]]]></description>
			<content:encoded><![CDATA[<p>In these more modern times of sexual equality, it may not be politically correct to talk about differences between men and women. Unfortunately, the medical profession cannot ignore the increasing volume of scientific evidence that there are important differences, particularly when it comes to pain management. In this, it is important to distinguish between biological sex and gender. There are visual tests for the presence or absence of reproductive organs, and lab tests for chromosomes that help to say whether this is a man or woman. Gender, on the other hand, is a list of the social roles society defines for people. This can be complicated when people choose to act or behave in ways considered more appropriate for the opposite sex. As an example of the problem, you only have to look at the complaints that Caster Semenya is not a woman. How can this muscular person from South Africa suddenly beat the word record for the 800m by one second and be a woman?</p>
<p>The last decade has seen a rapid rise in the volume of research into gender differences in the response to pain. There is clear evidence that women are more likely to consult a doctor about pain and to take drugs to relieve that pain. As a result, the national statistics show more women than men suffering from the more common medical conditions causing pain such as arthritis, irritable bowel syndrome, fibromyalgia, etc. In tests involving healthy volunteers, women are more likely to report higher levels of pain than men. This applies regardless of the other factors of age, race, ethnicity and religion. Interestingly, brain scans have shown that pain affects different parts of the brain. In women, the limbic area which also affects emotions is stimulated more than in men.</p>
<p>The speculation is that the differences in brain activity flow from early human development. Men were the stronger group with responsibility to fight to defend the community. This means being prepared to accept pain. Women were expected to respond to danger by nurturing and protecting the young, running away if necessary. Today, men remain less willing to admit to feeling pain and are reluctant to seek medical help. It does not matter whether this is a biological or gender difference, the statistical evidence for this unwillingness to seek help is absolutely clear. But, equally clear is that <a href="http://www.tramadolguidance.com/learn-more/when-it-comes-to-pain.html">tramadol</a> relieves the pain of both a macho man and an emotional woman. Even though there may be gender differences, the biological effect of tramadol is the same on a human body. It relieves moderate to severe pain. So, perhaps it is time for all men suffering in silence to overcome the cultural conditioning that threatens their self-esteem if they admit to pain. Once you have clearance from your local healthcare provider that there are no problems in you taking this drug, go online and <a href="http://www.tramadolguidance.com/">buy tramadol</a> from the privacy of your own home. This relieves the pain and preserves your image.</p>

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		<title>Troubleshooting your sex life</title>
		<link>http://www.spacandille.com/articles/troubleshooting-your-sex-life.html</link>
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		<pubDate>Sun, 03 Jan 2010 22:44:50 +0000</pubDate>
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		<description><![CDATA[When erection problems come your way, most men usually search in panic for the most effective medication that will help them get the spark back. But not that many think of the causes behind erectile dysfunction and try to dig out the root of the problem. Too bad, because this is just the right way [...]]]></description>
			<content:encoded><![CDATA[<p>When erection problems come your way, most men usually search in panic for the most effective medication that will help them get the spark back. But not that many think of the causes behind erectile dysfunction and try to dig out the root of the problem. Too bad, because this is just the right way to avoid erection problems altogether and make them milder even if they come. Erection problems are often caused by the overall state of your health and body, and if you want to enjoy a good sexual life for a longer time, here are some things you have to think about doing:</p>
<p><strong>First step: exercise is important</strong></p>
<p>Numerous studies indicate that exercising is directly related to the likelihood of developing impotence at a certain point. Men, who burn more than 200 calories daily by exercising are know to be less prone to erectile dysfunction and their testosterone levels are usually higher then in men who don&#8217;t exercise. However, there is a word of caution towards those who prefer to use biking as their exercise of choice - men riding bikes are twice as likely to have erection problems as other men. Doctors link this finding with the usual block and tension in the penile area, while riding bikes (both on road and in the gym), which affects blood circulation.</p>
<p><strong>Second step: forget about bad habits and fatty meals</strong></p>
<p>Erection strongly depends on the state of arteries in the penis, as a normal blood circulation will result in a good and stable erection. But with age, men tend to suffer from various blood vessel conditions, the most frequent of which is atherosclerosis. You may not notice it until you are will into your 50&#8217;s, as it will gradually affect the vessels in your entire body, not only those next to your heart. And that means that the blood circulation in the penile area is likely to be affected by the condition. That&#8217;s why preventing conditions such as atherosclerosis means you&#8217;re also preventing erection problems. Here are some things you should do to make sure you are less prone to blood vessel problems:</p>
<ul>
<li>Eat less fatty meals</li>
<li>Shed off those extra pounds</li>
<li>Quit smoking</li>
</ul>
<p>Of all things, smoking is probably the most negative factor influencing erection problems. So remember that each cigarette smoked makes your impotence closer and more evident.</p>
<p><strong>Third step: analyze the drugs you are taking</strong></p>
<p>Erection problems can be caused by certain drugs you are currently taking. So make sure to consult with your physician, especially if you are currently taking any of the following groups of drugs:</p>
<ul>
<li>Antidepressants</li>
<li>Hypertension treatments</li>
<li>Psychosis or anxiety pills</li>
<li>Heartburn medications</li>
<li>Prostate disease drugs</li>
<li>Cholesterol regulators</li>
</ul>
<p>Substances like alcohol, marijuana and steroids are also known to affect male sexual potency, so make sure you&#8217;re not abusing the.</p>
<p><strong>Fourth step: choose a treatment</strong></p>
<p>With so many drugs designed for treating male impotence you will surely find what works for you. Drugs like <a href="http://www.power-pills.com/info/troubleshooting-your-sex-life.html">Cialis</a> or Levitra are known to help in the majority of cases, so if you need a little boost, you can easily <a href="http://www.power-pills.com/">buy Cialis</a> or any other drug online - thanks to the numerous online pharmacies out there, it has never been easier to do that.</p>

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		<title>Fear can be overcome</title>
		<link>http://www.spacandille.com/articles/fear-can-be-overcome.html</link>
		<comments>http://www.spacandille.com/articles/fear-can-be-overcome.html#comments</comments>
		<pubDate>Sun, 03 Jan 2010 21:19:47 +0000</pubDate>
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		<category><![CDATA[Wandering Spider]]></category>

		<guid isPermaLink="false">http://www.spacandille.com/articles/fear-can-be-overcome.html</guid>
		<description><![CDATA[One of the most common causes of erectile dysfunction is performance anxiety. Put simply, as men age, they begin to lose confidence that the erections of their youth will continue. It only takes one or two failures to get an erection hard enough for penetration and the worry starts to build. Soon, the worry becomes [...]]]></description>
			<content:encoded><![CDATA[<p>One of the most common causes of erectile dysfunction is performance anxiety. Put simply, as men age, they begin to lose confidence that the erections of their youth will continue. It only takes one or two failures to get an erection hard enough for penetration and the worry starts to build. Soon, the worry becomes a self-fulfilling prophesy. The anxiety takes over and erections fade away.</p>
<p>If you asked men to identify all their phobias, fear of sexual failure would obviously be high on the list. So much male self-esteem is wrapped up in the ability to be successful in the bedroom. But there&#8217;s also a widespread fear of spiders. Rightly or wrongly, many men find the presence of a spider disconcerting if not actually frightening. This despite the fact that, in the northern hemisphere, almost all the varieties of spiders are completely harmless. It seems to have something to do with the number of legs and the speed of the creatures.</p>
<p>This is the time to start talking about Brazil. Not only has it hit the headlines because Rio has been selected as the venue for the Olympics in 2016, it&#8217;s also the home of Phoneutria nigriventer, better known as the wandering spider. For those of you who like statistics, this is one of the most venomous spiders in the world and it&#8217;s responsible for the deaths of many (no-one actually does a reliable count of the fatalities). However, there&#8217;s a very good reason for overcoming your fear of this spider. When it sinks its fangs dripping with venom into a man, it not only puts the victim on the road to possible death unless treated, it also causes a long-lasting erection. In theory, this could make it a very pleasurable way to die except the erection apparently grows painful over time.</p>
<p>Attracted by news of this spider, US scientists have been injecting the venom into rats. There&#8217;s now clear clinical evidence that an active component of the venom relaxes blood vessels. This makes it a potential life-saving drug to reduce high blood pressure and, as a side effect, also treat erectile dysfunction. Pharmaceutical companies are therefore lining up to investigate this venom. The reason for the interest is that it&#8217;s a completely different chemical from levitra and the other drugs currently used to treat erectile dysfunction. The idea of developing a completely different class of drugs from a natural source makes this a very attractive commercial venture.</p>
<p>Until the development work is completed and FDA approval won, men will just have to struggle on with <a href="http://www.levitraguidance.com/more-about-levitra/fear-can-be-overcome.html">levitra</a>. After all, it only produces six hours of sexual responsiveness from the &#8220;as needed&#8221; version taken by men with a wide range of different physical and psychological problems. In other words, <a href="http://www.levitraguidance.com/">levitra</a> effectively has the erectile dysfunction market sewn up and it will take something phenomenal from the spider to beat it. But the potential applications to treat diseases of blood vessels, high blood pressure and heart disease may make the spiders the overall winners. It is possible that overcoming the fear of spiders may really pay health and stock dividends in the long run.</p>

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	<li><a href="http://www.spacandille.com/mens-issues/why-you-should-quit-smoking.html" title="Why you should quit smoking (August 7, 2009)">Why you should quit smoking</a> (0)</li>
	<li><a href="http://www.spacandille.com/articles/what-are-the-main-psychological-causes-of-erectile-dysfunction.html" title="What are the main psychological causes of erectile dysfunction? (January 4, 2010)">What are the main psychological causes of erectile dysfunction?</a> (0)</li>
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</ul>

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		<title>The truth is finally here</title>
		<link>http://www.spacandille.com/articles/the-truth-is-finally-here.html</link>
		<comments>http://www.spacandille.com/articles/the-truth-is-finally-here.html#comments</comments>
		<pubDate>Sat, 02 Jan 2010 22:46:11 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Articles]]></category>

		<category><![CDATA[Acupuncture]]></category>

		<category><![CDATA[American College Of Physicians]]></category>

		<category><![CDATA[Anaesthetic]]></category>

		<category><![CDATA[Beginning Of Time]]></category>

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		<category><![CDATA[Classic Demonstration]]></category>

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		<category><![CDATA[Needles]]></category>

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		<category><![CDATA[Placebo Effect]]></category>

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		<guid isPermaLink="false">http://www.spacandille.com/articles/the-truth-is-finally-here.html</guid>
		<description><![CDATA[Perhaps we were all misinformed. Was there really a report that the Earth was round? Did it come out about the same time as that mad suggestion the Earth goes round the sun? It gets so confusing about what is true and what is theory. Science is supposed to be ahead of the game but. [...]]]></description>
			<content:encoded><![CDATA[<p>Perhaps we were all misinformed. Was there really a report that the Earth was round? Did it come out about the same time as that mad suggestion the Earth goes round the sun? It gets so confusing about what is true and what is theory. Science is supposed to be ahead of the game but. . . All of which brings me to a key fact about the effectiveness of medical treatment. Since the beginning of time, a significant part of every successful treatment has been the so-called placebo effect. This is where the patient so strongly believes the treatment will work that any treatment will be successful. Even though the patient is given a completely inactive pill, liquid to drink or cream to rub on to the affected area, the patient is still cured. It is the classic demonstration of mind over matter. People simply will themselves better. For example, acupuncture is used as an anaesthetic for major surgery in China. Patients lie with their eyes open and needles sticking into them while surgeons cut them open. They talk about the weather with the nurses. In the West, there is recent research showing acupuncture to be successful even though needles are stuck into the wrong points in the body. All it takes is a strong enough belief that the acupuncture will be effective.</p>
<p>This is a simple way of saying a society must trust its doctors. If physicians are to command respect and so inspire confidence in the treatments they prescribe, they must be seen to be in touch with the latest science. Their words must be full of truth. If they seem out-of-date or behind the times, why should we trust them when they tell us to favor a particular treatment? People vote with their feet. When it comes to something important, we all choose to see the people who are thought to be the best in their field of expertise. We want the best. This makes the most recent pronouncement of the American College of Physicians all the more worrying. This October, they felt sufficiently certain of the science to be able to issue a general advisory notice to all their members. From now on, ACP members are to act on the basis that erectile dysfunction should be treated with <a href="http://www.viagrabluepills.com/">viagra</a>.</p>
<p>So, all you poor patients can relax now. You no longer have to wrestle with your consciences as ACP members prescribe vacuum tubes and hormone injections for your ED. All that uncertainty whether to follow this advice has gone. Your doctor will now officially be allowed to prescribe a little blue pill to resolve your problem. Have all these leaders in scientific thought been hiding under a rock for the last ten years? What are they thinking? How can it inspire confidence in the medical profession to make a formal announcement today about something patently obvious to the rest of the world for the last ten years? This is an incredible moment in time. Ladies and gentlemen, the truth has finally come in from the cold. It&#8217;s official. <a href="http://www.viagrabluepills.com/viagra.html">Buy viagra</a> with confidence. It is better than all the old hormone treatments and other silly pieces of equipment that occasionally appeared in the bedroom. Pop a pill and your ED is gone!</p>

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	<li><a href="http://www.spacandille.com/mens-issues/about-the-placebo-effect.html" title="About the placebo effect (August 2, 2009)">About the placebo effect</a> (0)</li>
</ul>

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		<title>The noble analgesic</title>
		<link>http://www.spacandille.com/articles/the-noble-analgesic.html</link>
		<comments>http://www.spacandille.com/articles/the-noble-analgesic.html#comments</comments>
		<pubDate>Sat, 02 Jan 2010 07:20:50 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
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		<category><![CDATA[Noradrenergic]]></category>

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		<category><![CDATA[Prompt Solution]]></category>

		<category><![CDATA[Pure And Applied Chemistry]]></category>

		<category><![CDATA[severe pain]]></category>

		<category><![CDATA[Sufferings]]></category>

		<category><![CDATA[tramadol]]></category>

		<category><![CDATA[Tramal]]></category>

		<category><![CDATA[ultram]]></category>

		<guid isPermaLink="false">http://www.spacandille.com/articles/the-noble-analgesic.html</guid>
		<description><![CDATA[Pain is the most undesirable feeling people experience. The only thing that brings people to the physicians is pain. Mostly, people visit the doctor for getting relief from pain because of different reasons. Pain might differ from moderate to severe, according to the origin and severity degree of the origin.
Some pain might be a natural [...]]]></description>
			<content:encoded><![CDATA[<p>Pain is the most undesirable feeling people experience. The only thing that brings people to the physicians is pain. Mostly, people visit the doctor for getting relief from pain because of different reasons. Pain might differ from moderate to severe, according to the origin and severity degree of the origin.</p>
<p>Some pain might be a natural part of life. It may need taking care to handle and get relief. Some times your pain might be so bad and strong, that it becomes truly hard to handle and manage. In such cases, the only solution to problem is taking a very strong painkiller. Pain extirpating and management is an inherent thing for possessing and at fully enjoying the healthy life without needless sufferings. Pain effects are only negative for living. They retard mental stamina, body strength, general health and our overall peace.</p>
<p>To get rid from the pain we are usually using some treatments, such as painkillers, exercises and meditation.</p>
<p>While some painkillers might bring alternative harmful side effects, people are still going for this option frequently as it brings prompt solution. They go for pain reducing medicaments such as Tramadol. This treatment is an efficacious painkiller, with a method of action pretty much identical to those of the drugs (narcotics). It is the generic formulation of a painkiller known as Ultram. The International Union of Pure and Applied Chemistry (IUPAC) name of this medication is rac-(1R, 2R)-2-(dimethylaminomethyl) -1-(3-methoxyphenyl)-cyclohexanol. It is used for the treatment of moderate to severe pain of different sources.</p>
<p>This medicine is the typical synthetic opioid used for treating different kinds of pain. It possesses possible arrangements on the serotonergic, noradrenergic and GABAergic body systems. The medicine is the German Grunenthal GmbH pharmaceutical company&#8217;s valiable present to the humankind for pain eradication. This analgesic is also marketed under such trade name as Tramal. It is offered in both intramuscular and intravenous forms, that might be injected respectively to muscles and veins. You can also find it in oral preparations.</p>
<p>It is found as Tramadol hydrochloride (hydrochloride salt) which is commerced under Ultram brand name in the United States of America. Another form is Ultracet obtainable right next to acetaminophen. The dosage for consumption differs with pain degree occurred in the patient&#8217;s body. It has more or less ten percents of morphine&#8217;s effect, when injected by IV/IM channel. Oral dosage varies from 50 to 400 mg daily, sometimes even up to 600 mg daily in certain cases of severe pain.</p>
<p>As it is N- and O-demethylated to five separate metabolites, <a href="http://www.tramadolbliss.com/">Tramadol</a> endures hepatic metabolism by the way of cytochrome P450 isozyme CYP2D6. The most adverse of its side effects include drowsiness, vomiting, sweating, respiratory depression, and nausea. While many physicians refer this medicine to pain relief, in many cases according to the Ultram&#8217;s prescription, <a href="http://www.tramadolbliss.com/tramadol-prices.html">Tramadol</a> &#8220;may encourage physical and psychological dependence of morphine-type&#8221;.</p>

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</ul>

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		<title>The FDA changes the warning notices</title>
		<link>http://www.spacandille.com/articles/the-fda-changes-the-warning-notices.html</link>
		<comments>http://www.spacandille.com/articles/the-fda-changes-the-warning-notices.html#comments</comments>
		<pubDate>Fri, 01 Jan 2010 22:47:15 +0000</pubDate>
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		<category><![CDATA[Articles]]></category>

		<category><![CDATA[Adverse Side Effects]]></category>

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		<guid isPermaLink="false">http://www.spacandille.com/articles/the-fda-changes-the-warning-notices.html</guid>
		<description><![CDATA[Many people think the Food and Drug Administration&#8217;s (FDA) role is limited to licensing new drugs and medical devices, but it actually has a post-marketing role as well. Doctors and hospitals all round the US are required to report any and all adverse side effects to drugs. It&#8217;s not uncommon to find that drugs can [...]]]></description>
			<content:encoded><![CDATA[<p>Many people think the Food and Drug Administration&#8217;s (FDA) role is limited to licensing new drugs and medical devices, but it actually has a post-marketing role as well. Doctors and hospitals all round the US are required to report any and all adverse side effects to drugs. It&#8217;s not uncommon to find that drugs can pass through clinical trials involving only thousands of participants, but show side effects when millions start taking them. Obviously, many problems come from those who abuse the drugs in one way or another but, every now and again, serious problems emerge over time. Once a pattern emerges, the FDA can either change the labels on the drugs to give stronger warning to patients or, in the worst cases, withdraw the licenses for the drug to be used. Since withdrawal can have a dramatic effect on the manufacturer, the FDA prefers to improve the level of warnings unless the problems are too severe to ignore.</p>
<p>Doctors have been aware of the problems of serotonin syndrome (sometimes also called serotonin toxicity) for some years. It&#8217;s a potentially serious adverse side effect when people ingest too much serotonin. Perhaps it&#8217;s better to think of this as a form of poisoning caused when people take excessive dosages of one drug or mix different drugs together. The effects fall into four main classes:</p>
<ul>
<li>a change to metal status - you may become agitated, hallucinate or, in extreme cases, fall into a coma;</li>
<li>the body may start to function erratically and your blood pressure rises, your heart races and your body suddenly loses or retains heat;</li>
<li>loss of physical co-ordination; and/or</li>
<li>nausea, vomiting and diarrhea.</li>
</ul>
<p>In some cases, the result has been death, e.g. the high-profile case of Libby Zion in 1984 which produced a change in the law of New York limiting the working hours for medical postgraduates and requiring their close supervision by senior physicians at all times. Thus, the FDA is not reacting to a new problem, but merely increasing the visibility of the warning notices as it affects all drugs containing serotonin.</p>
<p>In this instance, the warnings affect <a href="http://www.tramadolbliss.com/blog/?p=17">tramadol</a> in the following ways. It always has been the case that an overdose of any of the opioid painkillers can cause this syndrome. Fortunately, this particular problem is relatively uncommon. Even those in the most severe pain understand the risks of exceeding the safe dosages are too dangerous to justify. Accidental overdose is almost unknown. So the most common problem arises with interactions between <a href="http://www.tramadolbliss.com/">tramadol</a> and other drugs with a serotonin content. The most dangerous combinations come with the classes of antidepressants called serotonin-norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and triptans. The syndrome can arise even though you take the safe prescribed dose of the painkiller. So the warning is not so much about the painkillers themselves, but to alert people not to self-medicate. Since the rise of the online pharmacy industry, too many people have been buying drugs without a prescription - that means without talking through the risks with a doctor. Obviously, a doctor with access to a person&#8217;s medical history would immediately identify the dangers and either change the dosages or change the drugs. When people rely on recommendations from friends or the information they glean from the internet to decide what drugs to take, they can be putting themselves at risk. Hopefully, this new warning will prevent problems and keep people safe.</p>

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</ul>

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		<title>Never lie about having acne</title>
		<link>http://www.spacandille.com/articles/never-lie-about-having-acne.html</link>
		<comments>http://www.spacandille.com/articles/never-lie-about-having-acne.html#comments</comments>
		<pubDate>Fri, 01 Jan 2010 20:22:29 +0000</pubDate>
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		<guid isPermaLink="false">http://www.spacandille.com/articles/never-lie-about-having-acne.html</guid>
		<description><![CDATA[Medicalization is a wonderful word. It means the process of taking a natural condition and convincing people that it&#8217;s a disease to be treated and cured by the medical profession. Once a condition is medicalized, the pharmaceutical industry can sell drugs, doctors and hospitals can charge fees. The cash registers just keep on ringing up [...]]]></description>
			<content:encoded><![CDATA[<p>Medicalization is a wonderful word. It means the process of taking a natural condition and convincing people that it&#8217;s a disease to be treated and cured by the medical profession. Once a condition is medicalized, the pharmaceutical industry can sell drugs, doctors and hospitals can charge fees. The cash registers just keep on ringing up the profits. Once this happens, there&#8217;s a kind of bandwagon effect. The condition suddenly becomes a lot more serious. It&#8217;s now a disorder or disease. For health insurance companies, it&#8217;s a pre-existing condition.</p>
<p>Now there&#8217;s a funny thing about health insurance companies. They are never shy about coming forward with new reasons for not paying out on their policies. One of their classic excuses is the &#8220;disclosure&#8221; rule. The law sounds quite reasonable. If you are sitting in your office and never get to meet the person applying for a health plan, you have to rely on the honesty of what the person says when you decide whether to write the policy. It&#8217;s a sad fact that some people are less than honest when they apply for policies. They forget the heart problem and declare themselves fit and healthy. Insurance companies therefore need the right to rescind the policy - to cancel it if the applicant failed to disclose information needed to assess the risk.</p>
<p>So now we come to the case of Otto Raddatz who, courtesy of his sister, became a famous victim after his death. She testified to a Senate committee about what happened and the story, in suitably dramatic form, was later picked up by President Obama in support of his campaign for healthcare reform. The facts are easy to state. Here was a man lining up to get surgery for cancer. The hospital appointment was booked when, surprise, the insurance company decided to rescind the policy. Why? Because Otto had failed to disclose the fact he had acne as a teen! This was a serious pre-existing condition and likely an indicator he would get cancer later in his life. His failure to disclose it justified rescission. Well, fortunately, his sister was an attorney and she got the state attorney general on the job. Six weeks later, the insurer reinstated the policy and Otto got his operation. This gave him six more years of life.</p>
<p>It&#8217;s sometimes odd to see how the world works. The medical profession goes to great trouble to convince everyone that acne is a disease. The pharmaceutical industry sells us <a href="http://www.forget-acne.com/">accutane</a> which is an almost always effective treatment, clearing the skin and restoring beauty during the first period of treatment. And then insurance companies accept this medicalization and require people applying for policies to disclose acne as a pre-existing condition. This is a logical and predictable progression. If doctors say acne is a disease, it must be a pre-existing condition and everyone should disclose it when they apply for health insurance! Do not be deceived! The Illinois attorney general does not fight for everyone. Otto was lucky that his sister was an attorney with the right political connections. So never lie about having acne! The risk of rescission is real. And while you have acne, rely on <a href="http://www.forget-acne.com/never-lie-about-having-acne.html">accutane</a>, the sure-fire way of solving the problem.</p>

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		<title>New research finds natural limits to the effectiveness of opioids</title>
		<link>http://www.spacandille.com/articles/new-research-finds-natural-limits-to-the-effectiveness-of-opioids.html</link>
		<comments>http://www.spacandille.com/articles/new-research-finds-natural-limits-to-the-effectiveness-of-opioids.html#comments</comments>
		<pubDate>Fri, 01 Jan 2010 07:48:23 +0000</pubDate>
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		<description><![CDATA[Once formed, habits are extremely difficult to break. It seems easier to go on as you have before and don&#8217;t change anything. This can become a serious problem when science gets in the way of the habits. If you look at the world of adverts in print and the media, you will see opioids recommended [...]]]></description>
			<content:encoded><![CDATA[<p>Once formed, habits are extremely difficult to break. It seems easier to go on as you have before and don&#8217;t change anything. This can become a serious problem when science gets in the way of the habits. If you look at the world of adverts in print and the media, you will see opioids recommended as the sure-fire drugs to use as painkillers, no matter what the pain. It carries on in the venerable tradition of the slogan, &#8220;Beecham&#8217;s Pills cure all ills&#8221;. The idea of a panacea - one pill to rule them all, as The Dark Lord of Mordor might have said - has been around since the beginning of time. This is fair game for the marketers to use when talking to the public, but the same thinking has entered the training manuals for the medical profession. Sit in lectures for student doctors and you will hear the same story that opioids are the first line of defense when it comes to moderate to severe pain. Once you have the source of the prescriptions in on the group think, the habit is almost impossible to break.</p>
<p>The monitoring and review process put in place after a drug is released into the market is designed to catch any unexpected side effects. If evidence of problems emerges, the FDA can require the manufacturer to change the warnings on the label or, in the worst cases, withdraw the drug from the market. But this monitoring process is not designed to catch the drugs that are ineffective. If no-one has an adverse reaction when taking it, no report is filed with the FDA. It&#8217;s safe so who cares whether it works. All this brings us to the Cochrane Collaboration. This is a non-profit group where researchers sift through and analyze existing published medical research to see whether there are any consistent patterns - what might not be apparent in one clinical trial involving two hundred participants might be identified when you compile the results from fifteen different trials, each involving two hundred participants. Two recently published Cochrane Reports have concluded that opioids should not be routinely prescribed to patients even with severe pain from hip and knee osteoarthritis.</p>
<p>In both Reports, the independent conclusions were that the adverse side effects outweighed the benefits and that <a href="http://www.tramadolbliss.com/blog/?p=16">tramadol</a>, as the leading opioid, was no more effective than the strongest NSAIDs. The first Report consolidated the results from ten trials involving a total of just over 2,250 participants and concluded that there was little pain relief and minimal improvement in mobility. With higher dosages, one in twelve participants experienced adverse side effects. The second Report consolidated the results from eleven trials involving 1,020 participants and found little difference between the effectiveness of <a href="http://www.tramadolbliss.com/">tramadol</a> and the placebo. This leads to a somewhat controversial conclusion. That doctors should not routinely prescribe opioids for the treatment of hip and knee osteoarthritis. There should be a careful discussion of treatment options including weight loss, physical therapy and exercise, and a detailed explanation of all the adverse side effects to be expected. This new research does not change the general acceptance of tramadol as an effective painkiller. All it does is confirm that there is no such thing as one pill to cure all ills.</p>

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